抄録
Eleven cows with ovarian hypofunction were treated with mixed injection of pregnant mare serum (PMS) and chorionic gonadotropin (HCG). The results obtained were reported and discussed as follows.
1. Eleven cows which had been diagnosed as ovarian quiescence, hypoplasia of ovarian-follicle or retained corpus luteum, were tested. The therapeutic agent used was a proprietary preparation called Gonamix, 400M. U.
2. Nine cows out of the eleven responded to these hormones, which promoted the growth of follicles and caused ovulation in eight cows and atresia in one.The remaining two cows were retreated with the same dose at 20days after the initial injection and showed the follicle growth which was followed by ovulation.
3. On treatment, seven cows out of the eleven manifested signs of estrus which were hardly distinguishable from the normal ones.In one case, however, they were less remarkable and more difficult to recognize than in four other cases. These results agree with those reported by YAMAZOUGHI.
4. Six cows out of the seven which presented estrous signs in the first or second treatment, were bred and four of them conceived. Two cows did not conceive and the remaining four which had not been bred became to show a regular estrous cycle after the treatment.Nine cows out of the ten which had been bred became pregnant in the end.
5. When the mixed therapy with PMS and HCG is compared with the single therapy with PMS, the former is better than the latter in the following point: The responses to the mixed therapy are generally milder and more reliable in causing ovulation.Moreover, the appearance of estrous signs can be anticipated with higher probability.
6. Finally, it was found that the mixed gonadotropin therapy was considerably effective for the treatment of ovarian hypofunction in cows.
