Abstract
Two 2-year-old hybrid Holstein-Friesian cows were found to be suffering from porphyria, or porphyrinopathy. They were very thin, showing retarded growth. They had teeth of filthy pink color, and excreted urine of light reddish-brown color. Their skin was normal. Anemia was pronounced and few erythrocytes were normal during the hot summer season. With the dissipation of summer heat and the shortening of daytime, there was a decrease in amount of excretion of porphyrin, and general conditions of health were improved with the appearance of normal erythrocytes.
Autopsy findings consisted of bone tissue of reddishbrown color, decrease in amount of bone tissue as a result of enlargement of the bone-marrow cavity, softening of bone marrow, and enlargement of the spleen. Bone tissue gave rise to a bright-red fluorescence when irradiated with ultraviolet rays.
