Administration of Glycuronic Acid and Its Excretion in Dairy Cows

Abstract

Adult dairy cows showing normal metabolism were injected with glycuronic acid (GA) by the intravenous and subcutaneous route. They revealed a transient sudden increase in urinary GA with in about six hours after injection. The GA which appeared in the urine was of free form in most part.
When those cows were administered with GA perorally, there was little change in urinary GA. Clinically, GA gave rise to no disturbances in adult dairy cows, so long as its dose did not exceed 25 g by the parenteral route or 200 g by the peroral route.