Abstract
A mixed Marek's disease and Newcastle disease live virus vaccine (MNV) was prepared from herpes virus of turkeys and strain B, of Newcastle disease virus, and examined for safety, immunogenicity, and cohabitation infectivity. The results obtained are as follows.
1. MNV was safe for SPF and commercial dayold chicks.
2. Both vaccine virus did not interfere with each other. MNV showed the same immune effect as Marek's disease vaccine and Newcastle disease vaccine inoculated independently.
3. MNV revealed a little better results when inoculated intraperitoneally than when inoculated intramuscularly or subcutaneously.
4. MNV exerted no influence upon Newcastle disease live virus vaccine inoculated later.
5. Infection with herpes virus of turkeys was found in one of the birds placed in the same house with those inoculated with MNV immediately after inoculation. Infection with Newcastle disease virus was demonstrated in none of these birds.
