Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Studies on Successive and Mixed Anesthesia with Xylasin and Ketamine Hydrochloride in Dogs
KATSUAKI TAKASE[in Japanese][in Japanese][in Japanese]
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1979 Volume 32 Issue 6 Pages 327-331

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Abstract
Dogs were anesthetized with 2mg/kg of xylasin (XN) and 10mg/kg of ketamine hydrochloride (KH) by two methods. In one method XN was injected intramuscularly and KH 15 minutes later (group I). In the other method XN and KH were mixed in the syringe and injected intramuscularly (group II). In both groups anesthesia lasted for 30-45 minutes after essentially the same lapse of time.
Emesis occurred to 50% of the dogs of group I soon after injection with XN and to 30% of those of group II several minutes after injection with the mixture. In both groups bradycardia was prevented by preliminary treatment with atropine sulfate. Body temperature decreased by about 1°C. Average femoral arterial pressure increased by 21% in group 115 minutes after injection with XN and by 24% in group II 15 minutes after injection with the mixture. The respiration seemed to have been inhibited only mildly. No marked changes were observed in the blood test in either group. Both methods were concluded to be used effectively for anesthesia in dogs.
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