Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
Pharmacokinetic Estimation of Sulfamonomethoxine Residue at the Site of Intramuscular Injection
MINORU SHIMODAT. HAYAMA
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1979 Volume 32 Issue 6 Pages 340-343

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Abstract
Sulfamonomethoxine (SMX) residues at the site of intramuscular (i.m.) injection in cattle and swine were pharmacokinetically estimated from blood concentration-time curves. Availability of SMX after i. m. injection was evaluated to be about 1 in both animal species. The rate of absorption expressed as half life was estimated to be 13.8 minutes for cattle and 26.6 minutes for swine. These results suggested that the residual concentration of SMX at the site of i.m. injection might be below 0.1 ppm within 10hours.
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