Therapeutic Effect of Thiopronine on Bovine Fatty Liver

Abstract

Thiopronine (2-mercaptopropionylglycine, MPG) was adminitsered to 63 Holstein cows with fatty liver. Of them, 34 were treated with only MPG (50-100ml/time) and 29 with a combination of MPG and some other dugs. As a result, 30 (88.2%) and 18 (62.1%), respectively, showed a clinical improvement with a milk yield recovery, no fatty droplets being detectedfrom the liver.
T recovered cows exhibited a reduction in serum NEFA, TG, ALP, T-Bili (p<0.01), and BUN (p<0.05). The poorly miproved cows presented an increase in serum GOT, GPT and γA-GPT (P<0.05).