Effects of Various Salts and Surface Active Agents on Ovicidal Activity of Iodine on Ascaris Eggs

Abstract

Ovicidal activity of iodine was observed in the acid solution of iodine and a 50% growth inhibtion dose (GID₅₀) ranged from 9.4 to 16.8μg/ml. It was hardly observed in the alkaline soultion. In the test of an anion of various salts, an increase in activity of iodine was observed in the following increasing order: chioric, sulfuric acid, citric acid and phosphoric acid ion.
ion. Moreover, an increase in activity of iodine was observed in the test of an anionic surface active agents, such as sodium lauryl sulfate, sodium lauryl benzenesulfonate and sodium dialkylsulfosuccinate, as well as in the test of the acid soultion. GID₅₀ ranged from 18.0 to 22.0μg/ml. An increase in activity of iodine on Ascaris eggs was observed in the test of sorbitane mono laurate (T-20) and stearate succharose fatty acid ester 1570 of 15 nonionic surface active agents examined. No activity of iodine was observed on cationic surface active agents.