1987 Volume 40 Issue 2 Pages 89-92
Four cows clinically affected with leukosis, 6 cows positive for antibody against leukosis virus, and 5 normal cows were examined for diagnostic utility of sialic acid (SA) and glycoprotein (GP) in bloods The serum concentration of SA was 55.6±5.0mg/dl in the nomal cows, 50.0±7.2 mg/dl in the antibody-positive cows and 71.4±14.2mg/dl in the leukotic cows.
In the leukotic cows, the serum levels of SA and GP a-globulin were higher, β-and γ-globulin lower than in the other cows. The serum concentration of toatl GP as hexose did not much differ among the three groups.
Changes in SA and GP were observed in one leukotic cow for 2 years.
After the clinical manifesration, SA and GP a-globulin increased and GP β-and γ-globulin decreased. As an indicator for the diagnosis of bovine leukosis, the assay of both substances seemed to be useful.
