Serum Levels of C-Reactive Protein in Dogs and its Simple Techniques for Measurement

Abstract

The serum levels of C-reactive protein (CRP) in apparently healthy dogs and those with various disorders or surgical traumas were determined quantitatively by enzyme-linked immunoabsorbent assay (ELISA) and semiquantitatively by slide reversed passive latex agglutination test (RPLA). The CRP values of 290 serum samples obtained by ELISA well agreed with those by RPLA (r=0.913). Semiquantification of CRP was possible by RPLA with serum, plasma, or whole blood. Canine CRP could not be determined by using the human-CRP measurement Kit.