Journal of the Japan Veterinary Medical Association
Online ISSN : 2186-0211
Print ISSN : 0446-6454
ISSN-L : 0446-6454
A Case of Canine Hepatoblastoma Accompanied by Hypercalcemia
Yoshihiro OHMICHIAtsushi HIRAKAWAYoshiaki TAKAHASHIHinako SHIBAYAMAKayo NOGUCHIMasaaki YAMAMOTO
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2000 Volume 53 Issue 4 Pages 221-224

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Abstract
hypercalcemia, and radiography revealed an abdominal mass. Experimentallaparotomy showed a large, solid mass originating from the liver. Because the mass was big and tended to bleedwhen manipulated, we abandoned complete excision and collected samples for histophathology. The patientdied 2 days after the operation. The mass was diagnosed as hepatoblastoma. Elevated parathyroidhormone-related protein (PTH-rP) and serum α-feto protein levels suggested that the PTH-rP secreted by hepatoblastomacells led to hypercalcemia in the patient.
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