2006 Volume 59 Issue 2 Pages 135-139
Six cases of swine lymphoma were investigated histologically and immunohistochemically, and were classified based on the new WHO classification for human lymphoid malignancies. CD79a was expressed in five cases, three of which were diagnosed as diffuse large B-cell lymphoma (cases 2-4). Cytoplasmic immunoglobulin (Ig) was detected in a few cells. The remaining B-cell cases were a precursor B lymphoblastic lymphoma (case 1) and a composite lymphoma (a combination of lymphoplasmacytic lymphoma and immunoblastic lymphoma)(case 5), and were characterized by positive reactivity for terminal deoxynucleotidyl transferase (TdT) and the production of IgM (λ), respectively. In a peripheral T-cell lymphoma (case 6), the neoplastic cells showed CD3ε positivity, but did not express TdT. These six lymphomas resembled the human counterpart neoplasms in their morphology.
