three-day-old Japanese Black calf was unable to bear weight on its right fore limb and could not walk. Palpation and radiography of the limb showed a short oblique fracture of the humerus and radial nerve damage. After a lateral open approach, a unilateral external fixator with a single bar was used to immobilize the fracture. The calf was weight bearing three days after surgery. Healing was observed by radiography at 51 days and the fixator was removed. The gait gradually returned to normal. The results suggested that the technique was useful for repairing a fracture when a plaster cast could not be used or when the bone is surrounded by heavy muscle.
A 24-year-old thoroughbred horse with a persistent purulent nasal discharge was diagnosed with empyema. Despite antibiotic medication, the discharge continued. On palpation, a small mass was noted in the right nasal cavity. The mass extended to the nostril with a continuous discharge. Swelling of the frontal face became apparent. On necropsy, the dorsonasal turbinate mucosa, which was yellowish and gelatinous, had significantly thickened (2.5cm×7cm×25cm in size). A mass formed at the tip of the thickened mucosal lesion was observed protruding outside the nostril. Histologically, the mass consisted of granulation tissue with abundant mucinous substance. The mass was diagnosed as a nasal polyp.
The phagocytic activity of monocytes in the peripheral blood was examined in dogs administered with C-UP III, a mixture of plant polysaccharides. C-UP III was administered at doses of 0.01, 0.02 or 0.05g/kg/day for seven consecutive days, and phagocytic activity of monocytes was analyzed by the mean number of ingested latex beads (LB) and the percentage of monocytes that ingested LB. As a result, the phagocytic activities of monocytes were significantly elevated on day 7 after the start of administration in all groups. On day 21, the monocyte activity in dogs fed 0.02 and 0.05g/kg/day was still significantly higher than the initial levels; however, the 0.01g/kg/day group showed only an increased number of ingested LB, the percentage of LB ingested monocytes was not significantly higher. When C-UP III was administered at 8.3mg/kg twice a day for three days, the number of ingested LB was significantly elevated on days 3 and 7, while the percentage of monocytes that ingested LB was significantly elevated on days 2, 3 and 7. As a consequence phagocytic activity increased from day 3. There was no change in the body temperature of the dogs on days 0-2 before and 15, 30 and 45 min after C-UP III administration. The authors concluded that the enhanced phagocytic activity of monocytes was a result of C-UP III administration and not of elevated body temperature.
A dog abdominal surrogate model for instructional exercises was evaluated to determine acceptance, by cooperation of two hundred and fifty-one fourth-year veterinary students at four universities in Japan. After practicing a celiotomy and intestinal anastomosis using the model, students' responses to a questionnaire were analyzed. Most students thought that the model was effective for acquiring basic surgical skills (99.2%) and necessary prior to surgical practice using live animals (96.8%). The major advantages of practical training using the model were effectiveness for acquiring basic surgical skills (40.8%), easy understanding of the structure (38.4%), reducing the need for live animals (21.6%) and multiple usage (14.8%). Meanwhile, more than half students (57.6%) suggested potential improvements of the materials and design of the model. The surrogate model used in the present study was well received by the students. We suggest that the model would be an acceptable alternative to live animals for certain basic surgical procedures.
Blood samples (serum or plasma) from ten dogs with multicentric lymphoma (ML) were tested for initial blood α1-acid glycoprotein (α1AG). Four of five dogs with ML that initially had normal or slightly elevated α1-acid glycoprotein (α1AG)(<900μg/ml) had complete remission without recurrence. In contrast, four of five dogs with ML that initially had α1AG>900μg/ml had significantly shorter complete remission times and unstable clinical condition. These findings suggest that serum oz, AG level can be used as a prognostic marker in dogs with ML
Seven clinical cases of regular scabies involving Sarcoptes scabiei var. canis infestation in dogs were treated with selamectin (6.0-11.0mg/kg) administered topically in a single spot to the skin of each animal's back at the base of the neck between the scapulae. All of the cases were free from pruritus, skin lesions and sarcoptic mange after treatment. During a follow-up period of approximately 12 months after treatment, no dog presented with a recurrence of scabies. No significant adverse reactions were noticed in any of the dogs. The results in this report suggest that a single dose topical administration of selamectin at the recommended dosage is sufficient to control canine regular scabies.
Six cases of swine lymphoma were investigated histologically and immunohistochemically, and were classified based on the new WHO classification for human lymphoid malignancies. CD79a was expressed in five cases, three of which were diagnosed as diffuse large B-cell lymphoma (cases 2-4). Cytoplasmic immunoglobulin (Ig) was detected in a few cells. The remaining B-cell cases were a precursor B lymphoblastic lymphoma (case 1) and a composite lymphoma (a combination of lymphoplasmacytic lymphoma and immunoblastic lymphoma)(case 5), and were characterized by positive reactivity for terminal deoxynucleotidyl transferase (TdT) and the production of IgM (λ), respectively. In a peripheral T-cell lymphoma (case 6), the neoplastic cells showed CD3ε positivity, but did not express TdT. These six lymphomas resembled the human counterpart neoplasms in their morphology.