Abstract
To clarify the utility of immunity profiling of dairy herds, we analyzed peripheral mononuclear cells and performed blood metabolic profiling of A, B and C dairy herds. The occurrence of peripaturient disease in Herd A and B was higher than it was in Herd C. In blood biochemical analysis, high non-esterified fatty acid (NEFA) was found in Herd A before calving. In herd B, levels of total cholesterol and glucose were higher compared with the levels in Herds A and C. In immunological analysis, the rates of CD4+/CD8+ and IFN-γ/IL-4 in Herd A was between one and four months lower compared with the rates in Herds B and C. These findings suggested that there is suppression of the cellular immunological function after calving in A dairy herd with insufficient nutriment feeding content during the dry period.
