An Estimation of Urine Albumin/Creatinine Ratio in Cats with Chronic Renal Failure

Abstract

The clinical utility of the urine albumin/creatinine ratio (UAC) in cats with chronic renal failure was studied using a simplified UAC analyzer. The measurement results for diluted feline albumin standard solution showed linearity, with the need of a conversion formula (y=1.28x+1.04) and the ability to measure the feline urine albumin concentration. In cats with chronic renal failure, the UAC changed parallel with the urine protein/creatinine ratio (UPC), and the Log UAC and Log UPC were significantly correlated (r=0.795, P<0.01). The Log UAC and the plasma creatinine concentration were not significantly correlated. In cats with chronic renal failure, the UAC was thought to have the same clinical utility as the UPC, and to be a clinical indicator for renal function.