放射性物質による家畜の障害に関する基礎的研究 : II. P³2の消化管部局所適用による障害

抄録

Studies were performed on radiation hazard of lecal irradiation applied to the digestivesystem. The P" which had been wrapped with polyethylene film was inserted into fourplaces of the digestive system of the rat by surgical operation. These places were theabdominal subcutaneous tissue, abdomirral cavity, liver, and small intestirue.No remarkable change was caused in rat when the source had been implanted into theabdominal subcutarteous tissue, even though the dose of isotope used for injection wasa lethal one. Intraperitoneal implantation of the source, so as to cover the intestinaltract, gave rise to such typical symptoms as loss in body weight and diarrhea, causingdeath of all animals clue to intestinal injury. In these animals, the effects of irradiation ongeneral symptoms, blood picture, and orgaru weight were studied. The difference in theeffect of irradiatioru between the two types of application, irrtraperitoneal irujection and localimplantation, was discussed.