Abstract
In December, 1962, tlae autlaors happened to encounter 3 swinte cases of pseudo-tuberculosis which broke otut int Tottori city. Pasteurella pseudotuberculosis was isolatedfrom the liver, spleen, lurngs, duodenum, rectum, and mesenteric lymphnodes of thesecases.The main clinical findings were dullness, inappetence, blood-stained diarrlaea, andremarkable edema in the eyelids and their neighboring areas, the mandibla, and thelower part of the abdomen.Macroscopically were observed miliary grayish-white spots in the lixer, spleen, andmesenteric lymphnodes, enteritis catarrhalis and diphtheroides, swelling and grayish-white-macular formation in the mesenteric lymphnodes, dilatation of the riglnt ventricleof the heart, remarkable general edema, moderate increase of ascites, hydropericardium, and yellowisln coloration of the general adipose tissues.Microscopically, the following findings were characteristic. Tltere were purulentand necrotic foci containing baciJIary masses and surrounded by thin granulation tissues, that is, pseudotubercules, in the lungs, liver, spleen, mesenteric lymphnodes, and Nymph-follicles of the large intestiute. On the other hand, the liver presented cellular foci, some of which contained one or a few giant cells resembling Langhanss giant cells.Both pseudotubercular and cellular foci were present in the periphery of sorne acini.Consequently, it was considered that these changes had spread via circulatiout of theportal system. In the mesenteric lymphnodes, such pseudotubercular foci as observedin the liver and spleen were few, and necrotic areas with bacillary masses were spreadmostly along the peritrabecular and subcapsular sinuses. Therefore, it was presumedthat the change had been spread to the mesenteric lymphnodes via the lymphatic stream.In the colon and caecum where tlae diphtheroid change was present, the lymphfollicleswere hyperplastic and pseudotubercular foci sometimes formed in them.It was considered that loss of the resistance caused by general steatitis autd parasi-tism of Balanti
