HISTOPATHOLOGY OF MUSCLE IN EXPERIMENTAL ACUTE SWINE ERYSIPELAS

Abstract

Histopathological investigation was carried out on the muscles of six swines origi-nated from specific-pathogen-free (SPF) swine and inoculated intradermally with Erysipelo-thrix insidiosa. Degenerative changes were demonstrated in most skeletal muscles of allthe cases, in the Iaeart muscle of four cases, and in the smooth muscle of the small in-testine of one case. The changes were the severest in skeletal muscle, especially in mm.femoris, mm. extremitatis thoracicae liberae, and mm. abdominis. Waxy changes weresometimes followed by fibrosis, calcification, and regeneration of muscle fibers. Vascularalterations and some toxic or mechanical effects of bacteria would be important in tlteInistopathogenesis of muscular degeneration.