The Japanese Journal of Veterinary Science
Online ISSN : 1881-1442
Print ISSN : 0021-5295
ISSN-L : 0021-5295
Effects of Tetrocarcin-A on Bovine Theileriosis in Japan
Masao OHTOMOKouichi YAMAZAKIShingo ITOKameo SHIMURAShinya SHIMIZUTetsuro MINAMIToru FUJINAGAKenjiro SHIMADA
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1985 Volume 47 Issue 4 Pages 581-587

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Abstract

The effects of tetrocarcin-A (TC-A) in intravenous administration were studied in calves which had been infected, naturally or experimentally, with Theileria sergenti. The doses of the drug used were 0.32 to 6.4 mg/kg (body weight). No effect was detected when the drug was administered 3 times at a dose of 0.32 mg/kg. Prasitemia was decreased, but the level did not reach to negative even when 3 doses at 3.2 mg/kg were given. The drug was effective at a dose of 6.4 mg/kg and negative parasitemia was maintained for at least 10 days when the calf was given 2 administrations. The negative parasitemia was maintained for at least 32 days when the calf was given 3 doses.

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