A Case of Feline IgA-Monoclonal Gammopathy Associated with Bence Jones Proteinuria

Abstract

IgA-monoclonal gammopathy associated with Bence Jones proteinuria was diagnosed in a 5-year-old female Persian cat. Serum electrophoresis gave a monoclonal peak in the slow γ-globulin region. Serum IgA level was extreamly high more than 10 times of normal value by single radial immunodiffusion. In the urine, two narrow and high peaks were found in the fast γ-globulin region by electrophoresis, and they were confirmed as Bence Jones (B-J) protein. Many tumor nodules were found on the peritoneum with ascites, though no excessive multiplication of plasma cells was observed in bone marrow.