Correlation between the Indirect Hemagglutinating Antibody and Protection of Mice against Clostridium chauvoei

Abstract

The indirect hemagglutination (IHA) titers of sera against sonic extract of Clostridium chauvoei paralleled the protection of mice immunized with blackleg vaccine. The titers of 1:8 or higher correlated with sufficient protection of mice to the challenge exposure. These results suggest that the IHA test may be useful as an aid for evaluation of protective potency of blackleg vaccine.