The Japanese Journal of Veterinary Science
Online ISSN : 1881-1442
Print ISSN : 0021-5295
ISSN-L : 0021-5295
A Preliminary Study for Development of an Inactivated Chuzan Virus Vaccine
Yoshiyuki GOTOYasuo MIURAYuji KONO
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1988 Volume 50 Issue 3 Pages 673-678

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Abstract
A preliminaly study for development of an inactivated vaccine for Chuzan virus was performed. The best propagation of the virus was observed in BHK21 cell cultures. The culture fluid after treatment with formalin had good immunogenicity in cattle and guinea pigs. Immunized calves did not develop leukopenia and viremia, which were observed in a control calf, after challenge inoculation.
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© The Japanese Society of Veterinary Science
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