Abstract
Particles concentration on a cross section in a fluidized bed has been qualitatively visualized by a capacitance CT during the drug coating and drying processes. As a result, the high concentration is located near the tube wall at the drug coating process. However, the concentration tends to be uniform on the cross section. The originality of the present study lies in the application of capacitance CT to particles movement in a fluidized bed in jet coating as a first step of active control of drug production in order to prevent agglomeration of cohesion particles in pharmaceutical industry. Finally, the CT image is compared with the DEM simulation qualitatively to discuss the availability.
