C210 円盤回転型バイオリアクターでの微細領域におけるせん断力の解析

抄録

Stem cell culture becomes a key technology for the medical treatment of patient and implant technology. In this process, the cell size and the rate of necrosis is influenced on the fluid dynamical condition, such as maximum flow velocity, shearing slress, Reynolds stress, etc. According to the previous repornt, the cell size was detenrmred by the turbulence ofthe flow, in which the Kolmogorov's scale becomes important parameter in cell culture. In the present study, velocity measurement was camied out in whole flow field and local area. From the experimental results, it was shown that the fluctuation of velocity and vorticity had Kolmogorov's scale. The estimated shear stress obtained from the velocity distribution showed a good agreement with the previous nivestigation.