新型コロナウイルス感染症（COVID-19）の急性期症状の改善後に亜急性壊死性リンパ節炎（菊池―藤本病）様の病態を呈した2症例

抄録

Patients with coronavirus disease 2019 (COVID-19) often present with multiple symptoms such as cough, dyspnea and olfactory dysfunction, however, cervical lymphadenopathy is a relatively rare clinical sign. We report two patients with COVID-19 who presented with a clinical picture similar to that of subacute necrotizing lymphadenitis (Kikuchi-Fujimoto disease) after improvement of the acute symptoms of COVID-19. As systemic steroid therapy was markedly effective in both patients, we speculate that the lymphadenitis could have been caused by an immune reaction during reduction of the virus titers. When cervical lymphadenopathy and recurrent fever are observed after improvement of the acute symptoms in COVID-19 patients, the possibility of a Kikuchi-Fujimoto disease-like condition should be considered and corticosteroid treatment undertaken if the symptoms are prolonged.