肺炎マイコプラズマ感染症に認められた血小板減少性紫斑病の1例

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A case of acute thrombocytopenic purpura due to mycoplasma pneumoniae (M. P.) infection is described. The patient, a 12 year-old girl, was admitted to our hospital because of a sudden onset of epistaxis and purpuric rash. She had been suffering from cough, rhinorrhea and fever of 10 days duration. On admission, there was a evidence of mucocutaneus purpura on the oralmucosa, lips, upper limbs and neck. Also, macrohematuria was detected. No jaundice, anemia nor lymphadenopathy were present. Platelt count on admission was remarkably decreased. Examination of chest X-ray on two occasion was normal. Direct and indirect Coombs test, Ham test, immune complex and platlet associated (P. A.) IgG were all positive. The cold hemoagglutinin test was positive. Elevated M. P. complement fixation titer and indirect hemoagglutinin titer were detected. The ELISA IgM antibody to M. P. was elevated and return to within normal limits 21 days lator. These findings seems to be compatible to the antibody production mechanism in M. P. infection.