抄録
The purpose of this study is to investigate the effect of telaprevir based-regimen on the renal function of HCV patients. The telaprevir based-regimen caused a transient and reversible decrease in eGFR in patients (n=17) who were enrolled in a phase 3 trial in Japan. In addition, we examined the relationship between baseline characteristics and the renal function of patients (n=25) after marketting. Age was significantly related to the renal dysfunction. The present result indicates that the kidney function of aged patients including creatinine elevation is required to be careful monitored.
