A new scoring system for prognostic stratification in patients with alcoholic hepatitis in Japan

Abstract

Using variables in some scoring systems for alcoholic hepatitis (AH), we generated a new scoring system (Japan Alcoholic Hepatitis Score: JAS). Its ability to predict outcome was compared with that of Glasgow alcoholic hepatitis score (GAHS) in the data of patients with severe AH during 2004-2009 in Japan. Fifty seven hospitals provided full demographic data on 141 patients with AH (Alive 90, Dead 51). JAS was more accurate than GAHS in predicting 100-day mortality (area under the receiver operating characteristic, 0.71 vs 0.61, respectively). Cut off value was 10. JAS allows the stratification of the risk of death in alcoholic hepatitis in Japan, and can help the management of patients with AH.