一成分系及び多成分系火災ガスの毒性の数理的解析

抄録

It is desirable to have a generally applicable numerical method to estimate the toxicity effect (or, for more practical purposes, allowable escape time from a burning building) without resorting to routine animal experiments. The present authors have formulated equations to calculate the toxicity effect using a new concept, the ‘effective concentration’. Constants in the equations, specific for individual toxic gases and combinations of them, have been computed from the results of animal experiments available in the literature. In these experiments mice were exposed to six diffeent toxic gases individually and to two- or three-component mixtures of them, and the incapacitation times were measured.