成長期下顎骨における高タンパク食の影響に関する X 線的, 光顕的および超微形態的研究 : 骨基質形成

抄録

It has been made clear that amounts of intake of calcium and protein greatly affect internal structure of the jaw at the growth stage. However, there are differences in the views made in the reports on bone construction related to the amount of calcium intake and the level of protein intake. Therefore, and investigation was made on the effect of hyperprotein meal on the mandible. The results were as follows : I. Roentogenographic and bone density findings In the control group, the alveolar bone showed even thickness at the surface of incisors, and trabeculae were densely arranged. In the hyperprotein meal group as compared with the control group, decrease in traveculae and reduction in thickness of the whole alveolar bone were seen. In bone density findings, no significant differences were found between the two. II. Analytical findings of Ca and P on the X-ray microanalyzer In characteristic roentogenograms, Ca showed higher concentration than P within the same trabecula. Furthermore, hardly any difference was found between the relative specific of calcium quantity and relative specific of protein quantity of the control and hyperprotein meal groups. III. Hematologic findings No changes at all were found in electorolyte in serum and in biochemistry examination. IV. Histopathological findings In the hyperprotein meal group as compared with the control group, woven bone and spongy bone decreased extensively and bone marrow expanded markedly. In the median alveolar bone and buccal alveolar bone, the periodontal membrane showed extensively irregular arrangements. V. Scanning electron microscope findings In the hyperprotein meal group as compared with the control group, many amorphous bone lacunae were seen, and the borders with the surrounding matrices were unclear, and collagen fibrils were distributed sparsely. On the basis of the foregoing findings, it is suggested that the formation of bone matrix decreases by maintaining intake of hyperprotein meal for an extended time for the mandible at the growth stage.