Four-point bend tests were conducted for Si3_4/S45C joints. Sensitivity analysis was also performed by the FEM method to clarify the influence of mechanical factors on the fracture strength. The results obtained are as follows: (1) The decrease in strength for the Si3N4/S45C joints compared with those for Si3N4/Si3N4 joints is well explained in terms of residual stresses and stress concentration near the interface in the joint. The fracture strength of the metal (S45C) used for the joint has no effect on that of the joint. (2) There is an optimum yield strength of an insert metal (Cu), although the residual stress decreases with decreasing the yield strength. (3) An alternative arrangement of the multiple joint layers is effective in reducing the residual stresses.