The clarification of the dissolving processes of oxygen bubbles in blood is important as a fundamental study on the development of an oxygenator. In this work, the combination of the equation of motion for a bubble in blood subjected to a pulsating pressure and the equation of oxygen diffusion is numerically calculated. Consequently, the effects of the pressure oscillation on the dissolution of oxygen bubbles in blood are elucidated. It is found that the bubbles in blood subjected to pulsating pressure shrink with the radial oscillation, and that bubble dissolution times are short. The oxygen diffusion in blood is promoted due to the effect of pressure pulsation.