The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
ABSTRACT
Protein Ubiquitination; A molecular switch for helper T cell differentiation
Daisuke Aki
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2018 Volume 67 Issue 3 Article ID: 67-002-ABST

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Abstract

We recently discovered an unexpected functional collaboration of NEDD4 family ubiquitin E3 ligase, Itch and WWP2 in the negative regulation of type 2 helper T cell differentiation. Here we would like to discuss how these two E3s function in this process.

(Presented at the 1965th Meeting, July 5, 2018)

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© 2018 by The Keio Journal of Medicine
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