Abstract
In this paper a polyethylene catheter was inserted into the efferent lymphatic of lymph nodes which have been thought to be a main route of release of lymph, including lymphocytes. The lymph from the popliteal lymph node was collected by the catheter, and changes of the number of lymphocytes in the efferent lymphatic from lymph node under lymphogenous administration of antigen were investigated. As the results, the following facts were obtained that in early stage after lymphogenous stimulation of the antigen, the lymphocytes of the lymphatic matrix of the node migrated directly into venous blood stream, and lymphocytes released through the efferent lymphatic were few or decreased in number.
