PERSISTENT ALBUMINURIA AND MENINGITIS CAUSED BY CONGENITAL CYTOMEGALOVIRUS INFECTION

A CASE REPORT OF CYTOMEGALIC INCLUSION DISEASE

Abstract

A case of congenital cytomegalic inclusion disease is described. The main manifestations were encephalomeningitis, mental retardation, neonatal hepati-tis, splenomegaly, and prolonged albuminuria. The diagnosis was established by cytomegaloviruria, high titers of complement fixation antibody to cytome-galovirus persistent during infancy, and a cytomegalia with intranuclear inclusion body in urine.
The hypothesis that albuminuria of long duration, and prolonged abnor-mality of the cerebrospinal fluid can presumably be ascribed to congenital cytomegalovirus infection is discussed.