北関東医学
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
Cl. tertium O(H) からの酵素標品の肺炎双球菌XIV型多糖体に対する化学的作用
山本 茂
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1965 年 15 巻 3 号 p. 205-213

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1. An enzyme preparation partially purified from Clostridium tertium O(H) has an ability to destruct a common antigen of poeumococcus Type X IV in human blood group substance as well as to destroy a common antigen of blood group substance in Diplococcus pneumoniae Type X IV polysaccharide.
2. After enzymic digestion, N-acetylglucosamine, glucose, and galactose were found as simple sugar in dialyzable portion in which amount of N-acetylglucosamine was larger than other two sugars. In addition, small amount of several oligosaccharides composed of such three sugars were liberated in the same portion.
3 A determinant structure of pneumococcus Type X IV antigenicity in human blood group substance was presumed to be β-N-acetyl-D-glucosaminoyl-1→3-D-galactose and also that of the common antigenicity of human blood group substance in Dip. pneumoniae Type X IV polysaccharide, to be the same disaccharide or a trisaccharide in which β-D-glucosyl-1 →4 was linked to nonreducing end of the disaccharide.

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