北関東医学
Online ISSN : 1883-6135
Print ISSN : 0023-1908
ISSN-L : 0023-1908
胃がんの腫瘍抗原と胃粘膜の臓器特異性抗原に関する研究
相沢 二夫
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ジャーナル フリー

1977 年 27 巻 4 号 p. 285-298

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1) Gastric cancer antigen was detected with rabbit anti-gastric cancer serum which was absorbed with pooled normal human plasma and pooled normal gastric mucosal extracts. The precipitation reaction was inhibited by D-galactosamine and cancer patient's sera. The gastric cancer antigenic substance was a glycoprotein and appeared on immunoelectrophoresis as a single line in the y-region. The gastric cancer antigen was not detected in normal gastric mucosal extracts and other normal organ extracts.
2) Gastric mucosal antigens were detected with rabbit anti-normal gastric mucosa serum which was absorbed with pooled normal human plasma and duodenum, jejunum, ileum and colon extracts. The precipitation reaction was inhibited by D-galactosamine. One of gastric mucosal antigenic substances was a glycoprotein and appeared on immunoelectrophoresis as a single line in the α2-region. It was detected in gastric cancer extracts.
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