ヒト臓器の P 式血液型抗原の分布と性状

抄録

1) The distribution of blood group P₁ antigens in human organs was investigated. P1 antigen was found in blood group P₁ kidney. Both group P₁ and P₂ kidneys contained much P antigens and lung, spleen and heart contained small amount of P antigens.
2) The each fraction corresponding to globoside and CTH (ceramide trihexoside) isolated from kidney showed P and P^k activities respectively.
3) Treatment of the globoside fraction from kidney with human liver's crude enzyme preparation (contained ß-N-acetylgalactosaminidase) caused the loss of P specificity and the appearance of P^k specificity.
As the above results, it was confirmed that blood group P antigens in kidney were identical with those in erythrocytes.