多核白血球のルミノール添加による Chemiluminescence の測定
1982 年 32 巻 2 号 p. 189-194
詳細
1982 年 32 巻 2 号 p. 189-194
Though there are some methods for detecting phagocytosis and killing, but most of them are tedious and skilled technique is needed. Recent reports suggested that luminol enhanced chemiluminescence had been useful in assessing intracellular and opsonphagocytic function with small number of polymorphonuclear leukocytes by simple method. This report described the chemiluminescence of polymorphonuclear leukocytes in the patients with recurrent otitis media, membranoproliferative glomerulonephritis and fibrosing alveolitis by this method.
The results were as follow :
1) Depressed chemiluminescence was observed in 17% of 6 patients with recurrent otitis media. 2) Depressed chemiluminescence was observed in 30% of 10 patients with membranoproliferative glomerulonephritis.
3) Measuring of the patient with fibrosing alveolitis, 2 years old girl, the chemiluminescence was low peak values, and opsonic activity of the patient's serum for staphylococcus aureus and E. coli were lower than that of normal control serum.
