Prostatic cancer is one of the most common malignant tumors in the field of Urology. The number of the patients is increasing rapidly and its importance as a mortal disease is getting attention. In 1985, we organized a registration system for prostatic cancer patients found in and around Gunma prefecture. In this study, we analyzed the clinical characteristics of the 295 patients registered from 1987 to 1988. The results were as follows.
1. Mean age was 74.5 years old and the number of the patients was the greatest in the eighth decade.
2. Voiding disturbance was the most common chief complaint, followed by pollakisuria and miction pain.
3. Stage and grade distribution were as follows. Stage A 20.3%, B 16.9%, C 15. 2%, D 47.6%, well differentiated 25.9%, moderately differentiated 49.6% and poorly differentiated 24.5 %, respectively. A statistically significant relationship between stage and grade was observed.
4. Bone was the most common metastatic site. The highest incidence of bone metastasis was in ribs, followed by lumbar vertebra, ilium, thoracic vertebra and ischium.
5. The value of PAP, ALP and ESR tended to be higher in the patients with bone metastasis and that of Hb lower.
6. The serum testosterone was decreased rapidly from the ninth decade.
7. Twenty patients were detected by mass screening. Most of these patients were in an early stage.
8. Most of the patients were treated by hormonal therapy. LH-RH agonists constituted 46.3% of the hormonal therapy.
