百日咳菌免疫血清の熱抵抗性について

抄録

It is known that there is difference in thermostability between various kinds of bacteria. In the present experiments, the thermostability of pertussal immune serum was investigated, because only few reports are known on this point.
1) The O agglutinin was more thermolabile than the K agglutinin; the former was rapidly destroyed by heating at 73°C, while the latter was ret destroyed at temperatures lower than 80°C.
2) The antitoxin was easily destroyed by heating at 73°.
3) The protective antigen, produced by passive immunization, was scarcely affected by heating at 73°C. This factor seems to be different from the antitoxin. The elucidation of this factor must awaite future researches by means of the factor serum and others.