ドライスキンとかゆみ

抄録

Itch has been defined as an unpleasant sensation that provokes the desire to scratch itch. The itch in dry skin such as xerosis and atopic dermatitis is antihistamin-resistant itch (intractable itch). The itch in dry skin is induced easily by weak stimuli such as mechanical, chemical or physiological stimuli (alloknesis). Alloknesis may be induced by lowering of itch threshold. One of the cause of this phenomenon is the elongation (invasion) of nerve fibers into the epidermis. In this paper the invasion mechanisms of nerve fiber into the epidermis and the management of itch in dry skin were discussed.