抄録
The liver specimens obtained from two patients with primary amyloidosis were examined with light and electron microscopies. One patient, considered to be in the early stage, showed minimal deposits of amyloid in the portal area and space of Disse. The other, being in advanced stage, had massive deposits of amyloid through the entire lobules, and the hepatocytes seemed to be compressed by them, resulting in hepatocellular degeneration. The cellular origin of amyloid still remains uncertain. From this study, however, it seemed that the reticuloendothelial cell, especially Kupffer cell, has a close relation to amyloid production.
