Abstract
The transplantation of experimental ovarian tumors induced by chemical carcinogenetic materials to rats and their sensitivity to carcinostatics were discussed.Among the rats of the same series to which tumors were tried to transplant subcutaneously, sarcoma was successfully transplanted in 2 lineages; one is in the 52nd generation and another is in the 44th generation at present.The tumors could be transplanted to both male rats and female rats of the same series, but the transplantation rate was different in early generations. Tumor formation was seen not only by transplanting tumor cells subcutaneously but by injecting them intraperitoneally.The sensitivities of the transplanted tumors to various carcinostatics were tested and Mitomycin C was found to have a surviving effect.
