抄録
Mitochondria prepared from rat liver were incubated with ultraviolet light exposed methyl linoleate. By the method of using anisotropic inhibitor (ethidium bromide), the negative charge of outer-side of inner membrane of mitochondria energized was found to decrease following incubation. The disorders of respiratory responses of mitochondria affected with UV exposed methyl linoleate was related with the membrane damage. The combination use of superoxide dismutase could restore the membrane disorders induced by UV exposed methyl Linoleate. Liposome form was essential for res-toring membrane damages. However, free enzyme (no liposome form) had no effect on alleviating membrane disorders. The possibility of using superoxide dismutase (liposome form) was suggested for preventing cellular damage induced by lipid peroxidation.
