Abstract
From the results of ICP determination in 6 cases of macrocrania, it has become evident that Lundberg's pressure wave (plateau wave, B wave) can be applied satisfactorily in the evaluation or abnormality under semi-closed conditions such as occur in infants. ICP dermination in cases of macrocrania with moderately enlargement of the ventricles is important for the recognition of pathologic changes. In paticular, the pressure variation and the amplitude changes during REM period seem to be an interesting index of the extent of the involvement of the venous function. An increased ICP during REM period was also observed in a patient with holoprosencephaly, having only brain stem formation morphologically, suggesting an important relationship between the brain stem and the increased ICP during REM period.
