CELL-MYCOBACTERIA-INFECTION SYSTEM

I. STUDIES OF THE EFFECTS OF VARIOUS KINDS OF SERUM ON THE PHAGOCYTOSIS OF MYCOBACTERIA BY L CELL

Abstract

Shepard has been making many contributions to the study of host-parasite relationships by researching the behaviours of parasites and host cells in the course of bacteria infection, especially acid-fast bacilli to the established HeLa cells. Mori presented results similar to that which were described by Shepard. Mitsuhashi et al. reported on the conditions influencing the infections of Salmonella enteritidis to L cells which were derived from mouse fibroblast and the morphological changes of cells and bacteria after infection. The purpose of this present paper is to describe the fundamental data in regard to the factors affecting the phagocytosis rate in the case of infection of acid-fast bacilli to the L cells.