Abstract
Periodic nanostructures were created on a polyethylene terephthalate (PET) film surface with a
femtosecond laser to control cell spreading. Controlling cell spreading on PET surface would contribute
to the creation of advanced biomaterials. The PET film was bonded with the Si wafer, as a pre-treatment.
A silicon wafer was irradiated with the femtosecond laser through the PET film. After the irradiation,
periodic nanostructures were produced on the PET film surface. The period and groove depth of the
periodic nanostructure on the PET were about 600 nm and 100 nm, respectively. In a cell test on the
PET film, cell spreading was observed with a fluorescence microscope. 71% of cells were spread along
the grooves on the PET.
