The Review of Laser Engineering
Online ISSN : 1349-6603
Print ISSN : 0387-0200
ISSN-L : 0387-0200
Femtosecond Laser Formed Periodic Nanostructures on PET Film Surface for Controlling Cell Spreading
Yuji SATOMasahiro TSUKAMOTOTogo SHINONAGAKazuyuki HARATakuya KAWARyuichiro SASAKI
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JOURNAL OPEN ACCESS

2015 Volume 43 Issue 11 Pages 772-

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Abstract

Periodic nanostructures were created on a polyethylene terephthalate (PET) film surface with a femtosecond laser to control cell spreading. Controlling cell spreading on PET surface would contribute to the creation of advanced biomaterials. The PET film was bonded with the Si wafer, as a pre-treatment. A silicon wafer was irradiated with the femtosecond laser through the PET film. After the irradiation, periodic nanostructures were produced on the PET film surface. The period and groove depth of the periodic nanostructure on the PET were about 600 nm and 100 nm, respectively. In a cell test on the PET film, cell spreading was observed with a fluorescence microscope. 71% of cells were spread along the grooves on the PET.

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© 2015 by The Laser Society of Japan
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