抄録
The scattering and diffraction of light limit biological stimulation or sensing performances. These fundamental
limitations are an open challenge in the field of biomedical optics. A recently reported class of
photoacoustic techniques addresses these challenges by non-invasively and actively manipulating the
light propagation inside biological samples. To successfully control light propagation, laser-induced
acoustic pulses produce a high refractive index contrast within samples without high-intensity pressure.
This review summarizes the light-guiding principle and applications to deep-tissue fluorescence excitation
and light-sheet fluorescence microscopy.
