PARTIAL PURIFICATION OF RICKETTTSIA MOOSERI WITH A CATION EXCHANGE RESIN

Abstract

1) By the use of an ion exchange resin, Amberlite XE-64 (mix IA), Rickettsia mooseri could be highly purified easily. This procedure seems to be superior to previously described methods of purification in view of its simplicity.
2) The purified rickettsial suspensions retained infectivity for embryonated eggs, acute lethal toxicity for mice, and hemolytic activity.
3) Purified rickettsia maintained their antigenicity in the complementfixation test.